Use Warning/Watch. Ethinyl estradiol may perhaps inhibit the clearance of benzodiazepines that undertake oxidation, thus raising serum concentrations of concomitantly administered benzodiazepines.
butabarbital will lower the extent or effect of diazepam by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Monitor.
Asista a todas las citas con su médico y a las de laboratorio. Su médico ordenará algunas pruebas de laboratorio para comprobar su respuesta al diazepam.
For patients using handled much more commonly than recommended, to lower chance of withdrawal reactions, use a gradual taper to discontinue therapy (a client-distinct plan must be used to taper the dose)
etravirine will decrease the extent or outcome of diazepam by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Observe.
巴比妥类药物(比如:苯巴比妥) • 苯二氮平類藥物(比如:地西泮) • 氨己烯酸,及托吡酯
Stay away from or substitute One more drug for these medications when achievable. Consider for lack of therapeutic influence if medication needs to be coadministered.
Neonatal withdrawal syndrome and signs suggestive of floppy infant syndrome linked to administration of benzodiazepines through the later stages of pregnancy and peripartum period of time have already been reported Benzodiazepines cross the placenta and should develop respiratory melancholy, hypotonia, and sedation in neonates; keep an eye on neonates exposed to therapy throughout pregnancy or labor for indications of sedation, respiratory depression, hypotonia, and feeding complications; keep an eye on neonates subjected to therapy for the duration of pregnancy for signs of withdrawal; manage these neonates accordingly Animal details
Keep an eye on Intently (1)oxcarbazepine will minimize the level or influence of diazepam by influencing hepatic/intestinal enzyme CYP3A4 metabolism.
dronedarone will increase the stage more info or influence of diazepam by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Observe.
地西泮脂溶性较高，肌肉注射吸收慢而不规则，也不完全，血浓度不稳定，其峰值血药浓度比口服还低，故临床上一般不宜采用肌肉注射的方法给药。
Oral: Info not accessible No dose adjustment recommended Except administered for prolonged interval; lessen dose in extended intervals
Alcohol together with diazepam may bring about a synergistic enhancement with the hypotensive Homes of benzodiazepines and Alcoholic beverages.[95]
debe saber que este medicamento le puede ocasionar somnolencia. No conduzca ningún vehículo ni opere maquinaria hasta que sepa cómo le afecta este medicamento.